Management Of Heart Disease with Ayurvedic Drugs
Heart diseases (Hrid Roga) have been elaborately discussed in Ayurveda. The five types of heart disease have been classified on the basis of Dosas. These descriptions and practices by physicians could be useful for management of present day challenges posed by the heart diseases.
Many studies have been conducted by premier Institutions of Ayurveda and Modern medicine and allied disciplines. The Council has taken up investigation on Ischaemic heart diseases- Anginas and post infarct status. A study on Congestive Cardiac Failure has also been undertaken.
Ischaemic Heart Diseases (I.H.D.)
After extensive studies on hypolipidimic potential of Guggulu and establishing its role in prevention of atherosclerosis and control of hyperlipidemia, the drug has been taken up for management of Ischaemic Heart Diseases. Another combination of Guggulu with Puskara mula has been developed and investigated.
1.Guggulu
•A preliminary study was conducted on 40 patients for a period of three months to evaluate changes in all the fractions of lipid. The crude drug was administered 12-16 gm. per day in divided doses in the patients suffering from lipid disorders obesity, coronary heart disease, hemiplegia etc. A progressive fall was recorded in all the components of lipids.
At the end of three months, the percentage of average fall was serum cholesterol 25.4% triglyceride 30%, phospholipid 21.5% and serum free fatty acid 35.1%. In addition to this fall in the serum lipids, reduction in body weight was also recorded which was approximately 1kg per patient per month.Simultaneously the clinical relief in the symptoms of hemiplegia and coronary heart diseases was also observed. One of the significant findings has been that in some of flatulence were ameliorated and functional status of the patients was improved. The overall results showed a positive response in over 80 percent of patients.
2.Puskara Guggulu:
• According to ancient Ayurvedic literature, Puskara mula is very useful in the treatment of respiratory and heart diseases.
• Dried and powered roots of Puskaramula (Inula racemosa Hook F.) were mixed to coarse granules of oleroresin of Commiphora wightii (Guggulu, Sodhita (purified) in triphala kasaya) to formulate the drug Puskara guggulu was administered in the divided doses of 8 to 10 gm. per day for a period of three to six months.
• The presenting clinical symptomatology along with ECG findings and biochemical parameters were recorded initially and afterwards for assessing the response to the therapy. Response of the treatment was found to be very encouraging in patients who completed the full course. The precordial pain, dysponoea and palpitation were completely absent after the treatment. Their ECG pattern returned to normal with considerable improvement observed through various biochemical parameters.
• The presenting clinical symptomatology along with ECG findings and biochemical parameters were recorded initially and afterwards for assessing the response to the therapy. Response of the treatment was found to be very encouraging in patients who completed the full course. The precordial pain, dysponoea and palpitation were completely absent after the treatment. Their ECG pattern returned to normal with considerable improvement observed through various biochemical parameters.
3. In further studies, 355 patients of CHD, with evidence of Ischemia (in ECG) and exertional angina, when treated with Puskara guggulu (1:1w/w) powder for a period of 6 months, 6-8 Gms. /day in divided doses, showed a significant fall in cholesterol, triglycerides and total lipids. Symptoms of CHD viz pericordial pain, dyspnoea, palpitation, hypertension, diabetes mellitus, giddiness, cough, anorexia and flatulence were ameliorated and functional status of the patients was improved. The overall results showed a positive response in over 80 percent of patients.
Karavira in management of Congestive Cardiac Failure
The drug has been administered in the form of tincture prepared from roots. Observation on 99 patients of Congestive Cardiac Failure due to Rheumatic Heart Disease, Hypertension, Mycordial infarction for 6 weeks. About 90% of patients showed relief and relapse was noted in about 20% of these patients.
25 patients as the control group and 110 patients the trial group, showed very good effects of drug in patients with coronary insufficiency. The precordial pain and dysponea on effort, cardinal features of the disease, were relieved completely in about 70% of the patients in the treated group and substantially reduced in the remaining patients.
The control group of patients did not show any appreciable change in their clinical condition. Simultaneously, there was a significant fall in various fractions of serum lipids-serum cholesterol (26.31%), phospholipid (26.84%), triglycerides (36.11%) and free fatty acids (37.94%). The electrocardiographic findings also showed improvement.
SOURCE http://ccras.nic.in/Research_Actvities/20081015_heart.htm
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