Management of Bronchial Asthma with Herbo Mineral Ayurvedic Drugs
Bronchial asthma is chronic debilitating disease of varied etiology. Various causative factors such as allergies due to dust, fumes and pollen grains along with genetic factors have been studied and investigated. The growing environmental pollution with rapid and extensive industrialization is also responsible for aggravation of this disease. The alarming rise in the incidence of this disease in metropolitan cities has posed a serious problem. Keeping these factors in view and also to find a simple and easily accessible treatment, the following studies were carried out.
Clinical studies
Study-I:
The two combinations of Naradiya Lakshmi Vilasa Rasa with Godanti Bhasma and Swasa Kesari (Kantakari with Godanti Bhasma) have been evolved and put on trial in separate groups of patients.
Dose
Group A:
This group constituted Naradiya Laksmi Vilasa Rasa and Godanti Bhasma in a dose of 500 mg. and 1 gm. respectively thrice a day.
Group B:
This group constituted Shwasa Kesari tablets (each tabletsof 500 mg.) three tablets thrice a day.
The efficacy of the treatment has been evaluated on the basis of clinical improvement i.e. changes in signs and symptoms of the disease. In addition, a quantitative assessment of primary functions tests such as vital capacity, peak flow rate, breath holding time etc. have also been undertaken. The data have been statistically analysed.
Results
Out of 783 patients studied with Shwasa Kesari, most of the patients showed good response. Only less then 5% showed poor effect on the disease. Laksmi Vilasa Rasa, Godanti combination was equally effective and about 8% did not show any affect of the therapy.
It may be concluded that:
Both groups of drugs for the treatment of Tamaka shwasa are quite effective.
The action of these groups of drugs, when given in the doses prescribed is marked; lesser doses may not show good results.
Both groups of drugs are safe and no toxic and side effects were noted during the study except that of feeling of thirst in 3% of the cases in Group B.
Beside the treatment, the patients of Tamaka Shwasa must follow the regimen of ‘Pathya’ and ‘Apathya’ (Do’s & Don’t’s).
Study-II:
Kantakari whole plant was studied on 151 patients. The drug was administered in the form of Kwatha (Decoction) in the dose of 30 ml. three times a day. The effect of the drug was evident in the most of the patients (59.09%) who completed the full course of 4 weeks.
Study-III:
Sirisa (Albizzia lebbeck Benth.) tvak (Stem bark) administered in the form of decoction was studied on 391 patients. A six-week course of the drug, 30 ml. three times a day has shown reasonably good response. 50% of the patients who completed the full course of treatment have shown definite relief.
source http://ccras.nic.in/Research_Actvities/20081015_Bronch_Hsth.htm
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| Id.No.2914 | |
| EFFECT OF SIMHANADA GUGGULU AND PUNARNAVARISTA IN TAMAKASHWASA (BRONCHIAL ASTHMA) – A CLINICAL STUDY | |
| * Parameshwarappa S. Byadgi ** Akash Chandra Tripathi | |
| Institute of Medical Sciences, Banaras Hindu University, Varanasi | |
| Abstract: Tamakashwasa(bronchial asthma) is characterized by wheeze,chest tightness, dyspnoea, cough. It manifests due to exposure to dust, pollen grains, cold weather etc. Mainly vata and kapha is involved along with rasadhatu. Due to abnormality in the homeostasis of dosha and dhatu leading to development of ama (mainly sama rasadhatugata malarupi kapha) resulting into genesis of various reactions inside the pranavaha srotas. Present study reveals the efficacy of Simhanada Guggulu, punarnavarista, kunjal karma, pranayam in the management of tamakashwasa (bronchial asthma). Encouraging statistical data suggest the effective management of tamakashwasa by the selected therapy. | |
| Key words: Tamakashwasa, Simhanada Guggulu, Punarnavarista, Kunjal Karma, Pranayama. | |
| * Lecturer, Department of Vikriti Vijnana, Faculty of Ayurveda ** (JR-II) Department of Vikriti Vijnana, Faculty of Ayurveda.
SOURCE http://www.ayurveduniversity.com/2008_1.php /////////////////////////////////////////////////////////////////// |
| Id.No.2821 | |
| A COMPARATIVE PHARMACEUTICO-PHARMACO-CLINICAL STUDY OF FORMULATIONS OF TULSI PILLS, TULSI ARKA AND TULSI AEROSOL ON TAMAKASHWASA | |
| * Vimal R. Joshi ** B. J. Pattagiri *** P. K. Prajapati | |
| Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar | |
| Abstract: Asthma is a chronic inflammatory disorder of the air ways in which many cells play a role, particularly mast cells, eosinophils and T-lymphocytes.1. Tulsi is one among Shwasahara Mahakashaya described by Acharya Charaka2. Here an attempt has been made to observe the effect of the drug Tulsi by different formulations namely Vati, Arka and Aerosol. The study showed encouraging results in patients of Shwasa by Tulsi Aerosol followed by Vati and Arka. | |
| Key words: Tulsi, Vati, Shwasa, Arka, Aerosol | |
| * M.D. (Ayu) Rasashastra, ** Lecturer, Dept. of R.S. & B.K. *** Reader & HOD, Dept.of R.S. & B.K. |
SOURCE http://www.ayurveduniversity.com/2007_2.php
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| Id.No.2733 | |
| A COMPARATIVE PHARMACO – CLINICAL STUDY ON ANTI-ASTHMATIC EFFECT OF SHIRISHARISHTA PREPARED BY BARK, SAPWOOD AND HEARTWOOD OF ALBIZIA LEBBECK | |
| * Mundeep Jaiswal ** P.K. Prajapati ***B.J. Patgiri ****B. Ravishankar | |
| Institute for Post Graduate Teaching & Research in Ayurveda, Gujarat Ayurved University, Jamnagar. | |
| Abstract: Shirisharishta is a compound formulation having main content as Shirisha. Shirisha (Albizia lebbeck Benth.) is a well known classical drug for the treatment of various types of diseases such as Shwasa, Kasa etc. The plant is reported to have various pharmacological properties like anti-asthmatic, antihistaminic, anti-protozoal etc. Most of the recent studies are reported about the pharmacological actions of it’s bark, leaves, pods and fruits, but almost negligible references about the pharmacological action of it’ heartwood are available. Nowadays Twak (bark) is commonly used for the preparation of Shirisharishta, but Sara (heartwood) is the part which is indicated in Asava Yoni. Shwasa Roga (Asthma) is one of the most common chronic diseases in the world. It may be defined as a disease in which the respiration is disturbed due to narrowing or obstruction in the channels. Bronchial asthma is a common disease affecting 10% to 20% of population. Considering the above facts in the present study Shirisharishta was prepared by Twaka (bark), Kastha (sapwood) and Sara (heartwood) of Shirisha. Pharmacologically Shirisharishta prepared by Sara shows significant result in anti-inflammatory and anti-tussive actions and significant increase in anti-histaminic activity while better activity profile in CMI suppression activity than the other two groups of Arishta. Clinical study on 41 patients also supports the experimental data in which Shirisharishta prepared by Sara shows better result in curing the disease Shwasa (Asthma). | |
| Key words: Shirisha (Albizia lebbeck); Sandhan Kalpana; Asava Yoni; Anti-asthmatic activity; Shwasa Roga | |
| * M.D. (Ayu.) Scholar, Dept. of R.S. & B.K. ** Reader & Head, Dept. of R.S. & B. K. *** Lecturer, Dept. of R.S. & B. K **** Head, Pharmacology Lab. |
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| Id.No.2932 | |
| EFFECT OF SHIREESHADI GHANAVATI IN THE MANAGEMENT OF TAMAKA SHWASA
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| * Shweta Agarwa ** M. S. Baghel | |
| Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar | |
| Abstract: Considering the high prevalence of the disease and the need to look for alternative medicine, a randomized open clinical trial on 29 subjects of Tamaka Shwasa (Bronchial Asthma), screened on the basis of clinical findings were allocated to two groups. Group A having 15 cases received the trial drug Shireeshadi Ghanavati (SGV) and 14 cases in Group B received Shwasa Kuthar Rasa (SKR) as a control drug. In SGV group, 13.33% of patients were observed with complete remission and 40% patients got marked improvement, 20% each were observed as improved as well as unchanged. The response was encouraging and left the scope for further study. | |
| Key words: Alternative Medicine, Randomized clinical trial, Tamaka Shwasa, Shireeshadi Ghanavati (SGV), Shwasakuthara Rasa (SKR). | |
| * M.D. (Ayu.), Department of Kayachikitsa** Director, IPGT & RA |
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A CLINICAL STUDY ON BRONCHIAL ASTHMA WITH AYURVEDIC MEDICINES D. PAHARI, P. C. TRIPATHI
INTRODUCTION:
Bronchial asthma is one of the oldest companion of human beings. It effects the population in general irrespective of age, sex, caste, religion, country etc and gradually found with an increasing trend. The knowledge of this disease is known to the physician of Indian system of medicine since vedic era. The concept of the disease with its management is found to be more descriptive and developed.
Scholars of various disciplines are working on the problem and various modern means and measures have been discovered. Even then the effective drug without any reaction couldn’t be established. Ayurveda is the reach source of the therapeutic measures that can control the disease. Out of such therapeutic measures a poly-herbal compound is selected for the benefit of the increasing number of asthma patients.
MATERIALS & METHODS :
The clinical study is conducted to evaluate the therapeutic value of a poly-herbal compound in established cases of Bronchial asthma. The present study consisted of 18 cases of Bronchial asthma. This study is conducted at S.V.S.P. Hospital, attached to the Institute of Post Graduate Ayurvedic Education & Research, Calcutta.
The patient was selected for the study from out patient department of the hospital after taking a short history of the patient. Some of the patients were admitted in-patients department of the same hospital. All the selected cases were carefully examined and records were maintained. To arrive at the diagnosis along with the history taking, Physical examinations and some investigations were done.
The investigations were as follows :
BLOOD : T.L.C. ; D.L.C. ; Hb% ; E.S.R. ; P.P.B.S.
STOOL : RE / ME
URINE : RE / ME
CHEST : X-Ray
PULMONARY FUNCTION TESTS :
(A) Breath holding time – measured by stop watch.
(B) Vital capacity-measured by an instrument called Spirometer.
(C) Peak expiratory flow rate measured with help of Peak flow meter.
After subjective & objective investigations the patient without any complications were only included in this study.
To all the patients a poly-herbal compound consisting of Talisadi Churna (as per the textual references) and Madhuyasti Churna in equal quantity was administered in the dose of 2 Gm thrice daily with water. The medicine was given for 8 weeks. The records of subjective improvements and objective improvements were recorded fortnightly. At the end of treatment the effect of the therapeutic resime on bronchial asthma was assessed.
RESULT & OBSERVATION :
In all the patients, subjective & objective criterias were recorded before treatment, during treatment and after treatment. The effect of the drug was assessed at the end of treatment.
Response of treatment in patients treats with Talisadi yoga.
Table showing the effect of Talisadi yoga on subjective features of Bronchial asthma.
| SNo | Clinical features | Present before treatment | Present after treatment | Percentage of relief |
| 1 | Coryza | 18 | 0 | 100% |
| 2 | Cough | 16 | 4 | 75.00% |
| 3 | Paroxysmal dyspnoea | 17 | 4 | 76.47% |
| 4 | Difficulty in expectoration | 17 | 5 | 70.59% |
| 5 | Filling tightness in chest | 10 | 2 | 80.00% |
| 6 | Insomnia | 12 | 2 | 83.33% |
| 7 | Restlessness | 18 | 4 | 77.78% |
| 8 | Rhales | 18 | 2 | 88.89% |
| 9 | Ronchi | 18 | 3 | 83.33% |
| 10 | Crepitation | 11 | 5 | 54.54% |
The effect of treatment on objective parameters in the patients of Bronchial Asthma, as observed in this study is given in the following table.
Table showing the effect of treatment on objective parameters in Bronchial Asthma.
| Objective parameters | Mean before treatment | Mean after treatment |
| Breath holding time | 18.6 sec | 26.8 sec |
| Vital capacity | 980 cc/sec | 1060 cc/sec |
| Peal expiratory flow rate | 196 l/min | 238 l/min |
From the above tables, study of the subjective and objective improvement can be compared and frpm these tables it is clearly observed that the subjective improvement is more than 54.54%. along with that the BHT, VC, and PEFR are found to be increased in all cases at the end of treatment. The improvement of these objective criterias ie. increase in BHT, VC and PEFR indicates improvement of the functional capacity of the lungs.
Conclusion:
This clinical study on Bronchial Asthma with Ayurvedic medicine is still continuing. During the present study the encouraging result which which we have seen so far during the work, is presented here. Talisadi Churna along with Madhuyasti shows a definite result in the case of Bronchial asthma. Further work will establish definitely the potentiality of the work and will pave the path of future workers.
D. Pahari – Research Scholar, Institute of Post Graduate Ayurvedic Education and Research
P.C. Tripathi – Lecturer, Institute of Post Graduate Ayurvedic Education and Research
SOURCE http://www.allayurveda.com/research_bron.asp
| Id.No.2733 | |
| A COMPARATIVE PHARMACO – CLINICAL STUDY ON ANTI-ASTHMATIC EFFECT OF SHIRISHARISHTA PREPARED BY BARK, SAPWOOD AND HEARTWOOD OF ALBIZIA LEBBECK | |
| * Mundeep Jaiswal ** P.K. Prajapati ***B.J. Patgiri ****B. Ravishankar | |
| Institute for Post Graduate Teaching & Research in Ayurveda, Gujarat Ayurved University, Jamnagar. | |
| Abstract: Shirisharishta is a compound formulation having main content as Shirisha. Shirisha (Albizia lebbeck Benth.) is a well known classical drug for the treatment of various types of diseases such as Shwasa, Kasa etc. The plant is reported to have various pharmacological properties like anti-asthmatic, antihistaminic, anti-protozoal etc. Most of the recent studies are reported about the pharmacological actions of it’s bark, leaves, pods and fruits, but almost negligible references about the pharmacological action of it’ heartwood are available. Nowadays Twak (bark) is commonly used for the preparation of Shirisharishta, but Sara (heartwood) is the part which is indicated in Asava Yoni. Shwasa Roga (Asthma) is one of the most common chronic diseases in the world. It may be defined as a disease in which the respiration is disturbed due to narrowing or obstruction in the channels. Bronchial asthma is a common disease affecting 10% to 20% of population. Considering the above facts in the present study Shirisharishta was prepared by Twaka (bark), Kastha (sapwood) and Sara (heartwood) of Shirisha. Pharmacologically Shirisharishta prepared by Sara shows significant result in anti-inflammatory and anti-tussive actions and significant increase in anti-histaminic activity while better activity profile in CMI suppression activity than the other two groups of Arishta. Clinical study on 41 patients also supports the experimental data in which Shirisharishta prepared by Sara shows better result in curing the disease Shwasa (Asthma). | |
| Key words: Kushtha, Ekkushtha, Psoriasis, Pathyadya vatak Vidangadi lepa | |
| * M.D (Ayu.) Scholar, Dept. of Kayachikitsa ** Sr. lecturer , Dept. of Kayachikitsa |
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